ARM YOURSELF WITH KNOWLEDGE: Breast cancer is a disease in which malignant (cancer) cells form in the tissue of the breast. It is considered a heterogeneous disease - differing by individual, age group, and even the kinds of cells within the tumors themselves. Women in the United States get breast cancer more than any other type of cancer except for skin cancer. It is second only to lung cancer as the leading cause of cancer death in women. Each year it is estimated that nearly 200,000 women will be diagnosed with breast cancer. More than 40,000 will die. Early detection is a key to survival. However, current diagnostic tests expose women to the potentially harmful effects of radiation - and often fail to detect cancer in the earliest stages. (Source: NationalBreastCancer.org)
DON'T HOLD YOUR BREATH . . . LITERALLY: Doctors have known since the Middle Ages that the aroma of breath can be a clue to what's wrong with a patient (i.e. there is a sweet smell of acetone in patients with uncontrolled diabetes, the fishy odor associated with advanced liver disease, as well as a urine-like smell that comes when kidneys are failing). In recent studies to detect breast cancer, a patient is asked to breathe though a small steel tube for two minutes. An absorbent pad in the tube captures a breath sample in which the contents are then analyzed to see which chemicals are present. As a patient breathes into the device, these compounds are trapped and examined by a sensor. Specific patterns in the compounds are then found and used to confirm the presence or absence of the disease. Researchers say that subtle but distinctive changes in the content for individual diseases, including different cancers, give each disease its own "breath fingerprint." The breath test distinguished between women with breast cancer and healthy volunteers with a sensitivity of 94.1 percent. (SOURCE: DailyMail.co.uk)
WAITING TO EXHALE: Researchers are currently making additions to their clinical database of breath data. They are trying to determine which compounds are most important for detecting breast cancer. That could help reduce the number of compounds tested. Because it can offer immediate results right in a physician's office, it is expected that the device will help increase early detection among those who do not have the resources for a mammogram, more easily conduct interval testing for those with a genetically high risk for breast cancer, and facilitate recurrence testing after breast cancer treatment.
* For More Information, Contact:
Georgia Institute of Technology
Abby Vogel – Media Relations
avogel@gatech.edu
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